Lung injury caused by one-lung ventilation during thoracoscopic pneumonectomy
Conditions
Interventions
RIPC-RIPostC group:Remote ischemic preconditioning combined with postconditioning
control group:No
Sponsors
Department of Anesthesiology, Second Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Pulmonary resection under thoracoscopy; 2. Intraoperative one-lung ventilation; 3. Aged more than 30 years and less than 60 years; 4. ASA is classified as I-III; 5. Normal or mildly abnormal lung function; 6. Voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. There is severe hypoxemia before surgery and oxygen inhalation is required (PaO2 <= 60mmHg); 2. Patients with thrombosis in the upper extremity itself; 3. Patients with coagulation dysfunction; 4. Peripheral ischemic vascular disease, blood system disease, upper extremity deformity, trauma, and dysfunction of the upper limbs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index;alveolar to arterial difference of oxygen tension (A-aDO2);Respiratory index;Dynamic lung compliance;Static lung compliance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factors;Incidence of pulmonary complications;ICU stay time;Postoperative hospital stay;Postoperative mechanical ventilation time; | — |
Countries
China
Contacts
Public ContactGao Changjun
Department of Anesthesiology, Second Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed