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A prospective randomized controlled study of mobile bearing knee replacement and fixed bearing knee replacement in the treatment of medial knee compartment osteoarthritis

A prospective randomized controlled study of mobile bearing knee replacement and fixed bearing knee replacement in the treatment of medial knee compartment osteoarthritis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051230
Enrollment
Unknown
Registered
2021-09-16
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthritis

Interventions

Mobile Bearing Knee Replacement Group:Mobile Bearing Knee Replacement Group
Control Group:Fixed Bearing Knee Replacement Group

Sponsors

Shanghai Yangpu District Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Anteromedial osteoarthritis, no extra-articular deformity; 2. The anterior cruciate ligament and collateral ligament are in good condition; 3. The thickness of the lateral compartment cartilage is complete; 4. The valgus stress can be corrected when the varus deformity is flexed at 20 degrees; 5. The flexion rigidity deformity is less than 15 degrees; 6. Subjects or their guardians agree to participate in this trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Not having legal capacity or limited legal capacity; 2. Knee joint infection, tuberculosis or tumor-related diseases; 3. Serious primary diseases of important organs; 4. Severe bleeding or bleeding tendency, such as active peptic ulcer, intracranial hemorrhage, trauma or other bleeding; 5. Suffering from autoimmune diseases such as rheumatoid arthritis; 6. Persons with active infectious diseases or connective tissue diseases such as hepatitis A, hepatitis B, AIDS, tuberculosis; 7. Any other situation that the investigator considers unsuitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
Oxford Knee Seessment score;Range of Motion;American knee society score;Risk of early complications or early mortality;

Countries

China

Contacts

Public ContactTu Yihui

Shanghai Yangpu District Central Hospital

tuyihui2010@126.com+86 13818148186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026