colorectal cancer
Conditions
Interventions
case series:Nil
Sponsors
Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 70 years, regardless of gender; 2. Patients who are clinically diagnosed as colorectal cancer and need systemic anti-tumor therapy after clinical evaluation, including: chemotherapy, targeted drug therapy, signal transduction inhibitors , Immunotherapy, or other treatments that are not specified in the research protocol but meet the definition of systemic anti-tumor therapy; 3. Fresh tumor tissue samples in vitro that meet the requirements can be obtained. The source of the samples is >=1, and the sources include surgical resection, puncture biopsy, Colonoscopy biopsy; 4. The number of lesions that can be evaluated according to RECIST vl.l is >= 1; 5. Able to understand the relevant content in the informed consent form, willing to cooperate with treatment, follow-up and other examinations, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with primary cancers other than colorectal cancer; 2. Patients who are receiving or have previously received systemic anti-tumor therapy; 3. Patients undergoing radiotherapy; 4. Patients who need to receive radiation therapy in addition to systemic anti-tumor therapy; 5. Female patients who are pregnant or breastfeeding; 6. Patients who are participating in other studies; 7. There are other situations that are not suitable for participating in the research (if such a situation exists, it should be specified in the research medical record and case report form).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pdo modeling success rate(%); | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug sensitivity test index after successful PDO modeling; | — |
Countries
China
Contacts
Public ContactZhou Yanbing
Affiliated Hospital of Qingdao University
Outcome results
None listed