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Efficacy of compound betamethasone injection combined with ropivacaine in ultrasound-guided thoracic paravertebral nerve block for postoperative analgesia in patients undergoing thoracoscopic surgery

Efficacy of compound betamethasone injection combined with ropivacaine in ultrasound-guided thoracic paravertebral nerve block for postoperative analgesia in patients undergoing thoracoscopic surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051201
Enrollment
Unknown
Registered
2021-09-15
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing thoracoscopic lobectomy

Interventions

Group RD:thoracic paravertebral nerve block with compound betamethasone
Group R:thoracic paravertebral nerve block

Sponsors

Affiliated Hospital of Nantong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. 18-70 years old; 2. ASA classification I-III; 3. BMI: 18.5-28Kg/m2; 4. Type of operation: elective thoracoscopic lobectomy; 5. The patient and (or) family members have signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Allergic to local anesthetics or glucocorticoids; 2. Preoperative use of opioids; 3. Severe coagulation dysfunction; 4. Severe heart, lung, liver and kidney insufficiency; 5. History of immunosuppressive therapy such as radiotherapy, chemotherapy and glucocorticoids or immune system diseases; 6. Peptic ulcer; 7. Recent history of gastrointestinal anastomosis; 8. Have a history of thoracic surgery; 9. The existence of central nervous system disease or peripheral neuropathy; 10. Receive blood transfusion during the perioperative period; 11. Patients with other steroid hormones should be used with caution: such as fractures, wound repair period, corneal ulcers, hyperadrenocorticism, diabetes mellitus, pregnant women.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Countries

China

Contacts

Public ContactQin Yibin

Affiliated Hospital of Nantong University

572537172@qq.com+86 13815212600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026