Effect of electrical impedance guided PEEP in reducing pulmonary complications after craniotomy

Clinical application of pulmonary electrical impedance tomography in individualized ventilation strategy for patients undergoing craniotomy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051200

Enrollment

Unknown

Registered

2021-09-15

Start date

2021-09-01

Completion date

Unknown

Last updated

2022-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pulmonary complications

Interventions

P6 group:Positive end-expiratory pressure of 6cmH2O

Pi group:individualized positive end expiratory pressure

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Supine craniotomy patients; 2. Aged 18-65 years; 3. ASA I-II level; 4. 18.5 < BMI < 28; 5. Patients who agree to participate in this study and sign the informed consent for anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients with chronic lung disease or pneumonia within 1 month before surgery; 2. History of lung surgery; 3. Patients with a history of smoking; 4. Patients with abnormal cardiac function; 5. Those with symptoms of intracranial hypertension; 6. Preoperative CT or MRI examination showed that the midline was shifted and the ventricle was obviously compressed.

Design outcomes

Primary

Measure	Time frame
Incidence of pulmonary complications;	—

Secondary

Measure	Time frame
Lung ultrasound score(LUS);regional brain oxygen saturation, rScO2;arterial oxygen pressure(PaO2);Severity score of pulmonary complications;	—

Countries

China

Contacts

Public ContactLiu Hairui

The Second Affiliated Hospital of Soochow University

hrhr218@163.com+86 13584820904

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026