Sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged >=65 years; 2.Older people are diagnosed as sarcopenia according to the criteria for AWGS: appendicular skeletal muscle mass index (ASMI) < 7 kg/m2 for male (M) and <5.7 kg/m2 for female (F), using bioelectrical impedance analyzer (BIA); handgrip strength (HGS), M: < 28 kg, F: <18 kg; and/or gait speed (GS) <1 m/s by 6-meter walk test (6MWT); 3.The participants without following serious diseases, such as uncontrolled hypertension, hyperlipidemia, hyperglycemia, and diabetes; 4.The participants without following untreated diseases, such as gallstones or kidney stones, and infectious diseases; 5.The participants have no regular exercise habit for more than 3 months.
Exclusion criteria
Exclusion criteria: 1.The participants have absolute contraindication for exercising, such as deep venous thrombosis and/or blood clotting disorders; 2.The participants have serious cognitive impairments that effect the assessments and communication by researchers, such as dementia, mental illness 3.The participants suffered from serious diseases affect the assessments and interventions, such as musculoskeletal diseases (such as fracture, dislocation, osteoporosis, rheumatoid arthritis) and disability (such as loss of hands, feet or limbs); 4.The participants have serious spinal diseases or surgical history, such as vertebral fracture, inflammatory joint disease, ankylosing spondylitis, spondylolisthesis, rheumatism, cauda equina syndrome, tumor; 5.The participants have the history of following cardiovascular diseases, such as stroke, heart failure, coronary heart disease, epilepsy; 6.The participants who have taken the following drugs regularly in recent 3 months: antiplatelet agents (such as aspirin, aggrenox, cilostazol, eptifibatide, ticlopidine, and tirofiban), anticoagulant drug and analgesic drugs; 7.The participants have other diseases, which is judged by the professional doctors that participation in this study is not recommended; 8.The participants who dont sign the informed consent before the beginning of experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower limb muscle strength; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometric Measurements;Muscle mass;Handgrip strength;Physical performance;quality of life; | — |
Countries
China
Contacts
Chongming branch of Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University