Hepatocellular carcinoma
Conditions
Interventions
Experimental group:PVA particles were used to block the diverging channel
The control group:CalliSpheres microspheres were used to embolize the shunt with bleomycin
Sponsors
The First Affiliated Hospital of Henan University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. Liver function Child Pugh A/B (= 9.0g/dl, neutrophils >= 1.5 x 10^9/L, platelets>=50x 10^9/L; serum albumin >= 28g/L, total Bilirubin < 34.2µmol/L, alanine aminotransferase, aspartate aminotransferase < 5 times the upper limit of normal, blood urea nitrogen, creatinine < 1.5 times the upper limit of normal, INR < 1.7 or prothrombin time prolongation < 4s.
Exclusion criteria
Exclusion criteria: 1. Accompanying other malignant tumors; 2. The normal liver volume is less than 40% of the total liver volume; 3. ECOG score >= 2 points; 4. Patients with severe cardiovascular and cerebrovascular diseases; 5. Patients with severe infection; 6. Patients with severe coagulation dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| objective response rate;disease control rate;Overall survival; | — |
Countries
China
Contacts
Public ContactWang Tong
The First Affiliated Hospital of He'nan University of Science and Technology
Outcome results
None listed