Skip to content

Effect of multimodal rehabilitation paradigm on cerebral functional reorganization in stroke patients based on fNIRS

Study on dynamic quantitative evaluation of motor dysfunction and pattern of brain functional reorganization by functional near-infrared spectroscopy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051148
Enrollment
Unknown
Registered
2021-09-15
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Group 1:Multi-target repetitive transcranial magnetic stimulation (rTMS)
Group 2:Multi-target rTMS combined with limb movement rehabilitation training
Group 3:Multi-target functional electrical stimulation (FES)
Group 4:Multi-target FES combined with limb movement rehabilitation training

Sponsors

National Research Center for Rehabilitation Technical Aids
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The first stroke, diagnosed by head CT or MRI; 2. The onset time is between two weeks and six months; 3. There is mild, moderate or severe motor dysfunction; 4. The patient has no obvious cognitive and speech dysfunction.

Exclusion criteria

Exclusion criteria: 1. History of traumatic brain injury or brain tumor in the past; 2. Complicated with severe heart, lung, liver, kidney dysfunction or other serious physical diseases; 3. Past epilepsy and family history of epilepsy; 4. Metal implanted in the human body such as pacemaker, metal in the skull, etc.; 5. New infarction or secondary bleeding occurs, and the condition deteriorates; 6. Those with severe cervical vertebral disease, including severe cervical conical canal stenosis and cervical spine instability.

Design outcomes

Primary

MeasureTime frame
Cerebral oxygenation;Clinical functional scale;

Countries

China

Contacts

Public ContactLi Zengyong

National Research Center for Rehabilitation Technical Aids

lizengyong@nrcrta.cn+86 10 58122886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026