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A randomized, controlled, prospective study on the immune function of peripheral blood after docetaxel combined rocaltrol at a dose of in the treatment of advanced non-small cell patients

A randomized, controlled, prospective study on the immune function of peripheral blood after docetaxel combined rocaltrol at a dose of in the treatment of advanced non-small cell patients

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051135
Enrollment
Unknown
Registered
2021-09-14
Start date
2020-01-16
Completion date
Unknown
Last updated
2022-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tumor

Interventions

Group A:docetaxel
Group B:docetaxel+rocaltrol

Sponsors

The First Affiliated Hospital, Jinan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years when signing the Informed Consent Form (ICD); 2. According to WHO standards, advanced NSCLC has been diagnosed in the past for at least 6 months; 3. Resistance or relapse; 4. 25 OH Vitamin D<30 ng/mL; 5. Willing and able to comply with the research process of the program; 6. Be able to understand and sign the study informed consent, if it is illiterate, willing to make a handprinting on the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women; 2. Those with organ failure; Heart: Grade III and Grade IV; Liver: Reach Grade C of Child-Turcotte liver function classification; Kidney: renal failure and uremia stage; Lung: severe symptoms of respiratory failure; Brain: people with impaired consciousness. 3. Patients with a history of organ transplantation; 4. People with uncontrollable infectious diseases or other serious diseases, such as HIV positive; 5. Patients with systemic autoimmune diseases or immunodeficiency diseases; 6. Patients with allergies; 7. T cell tumors, such as T cell lymphoma, etc.; 8. Chronic diseases that require immune preparations or hormone therapy; 9. Participated in other clinical trials in the past 30 days.

Design outcomes

Primary

MeasureTime frame
complete response;

Countries

China

Contacts

Public ContactXinhai Zhu

The First Affiliated Hospital, Jinan University

jnuyfg@163.com+86 18529366871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026