non-small cell lung cancer (NSCLC)
Conditions
Interventions
Group 1:Systematic Lymph Node Dissection
Group 2:Lobe-specific Lymph Node Dissection
Sponsors
The First Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
20 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20-79 years; 2. Preoperative CT showed that the tumor diameter was less than or equal to 1 cm, and the nodule solid component ratio (consolidation to tumor ratio, CTR) was greater than or equal to 0.25; 3. Preoperative CT manifestations are peripheral solitary nodules or associated lesions with micro-invasion and below; 4. Intraoperative frozen diagnosis of invasive lung adenocarcinoma with negative MP and S subtypes (=1.5L or FEV1/forced vital capacity >=60%], which can tolerate both segmentectomy and lobectomy; 7. Eastern Cooperative Oncology Group (ECOG) physical status score of 0-2; 8. Voluntarily participate and sign the informed consent form, and be able to comply with the research method plan and other program requirements.
Exclusion criteria
Exclusion criteria: 1. Preoperative imaging examination or mediastinal lymph node puncture indicated that the preoperative lymph node was positive; 2. Those with distant metastasis or pleural effusion or ascites were found in preoperative examination; 3. Intraoperative frozen diagnosis of carcinoma in situ, minimally invasive adenocarcinoma or papillary carcinoma; 4. Those with severe damage to heart, liver or kidney function; 5. History of lung surgery or radiotherapy; 6. Extensive adhesion of the pleura; 7. Patients who are pregnant or breastfeeding; 8. Received any form of anti-tumor treatment before surgery, including interventional chemoembolization, ablation, radiotherapy, chemotherapy, and molecular targeted therapy; 9. History of other malignant tumors within 5 years before enrollment; 10. Other uncontrollable inoperable patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease-free survival;Overall survival;Daily average postoperative thoracic drainage ;Postoperative extubation time ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time;Intraoperative blood loss ;Intraoperative blood transfusion ;Average length of stay ;Postoperative complications ; | — |
Countries
China
Contacts
Public ContactZhang Guangjian
The First Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed