None listed
Conditions
Interventions
Group 1:Ciprofol 8 mg/kg/h
Group 2:Ciprofol 6 mg/kg/h
Group 3:Propofol 40 mg/kg/h
Sponsors
Fudan University Zhongshan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult patients over the age of 18, gender is not limited; 2. Patients undergoing surgery requiring intravenous anesthesia (including patients undergoing colonoscopy or gastroscopy, patients undergoing endoscopic retrograde cholangiopancreatography, and patients undergoing bronchoscopy); 3. Voluntarily sign or be able to provide informed consent.
Exclusion criteria
Exclusion criteria: 1. Those with contraindications to deep sedation/general anesthesia or those who have had a history of sedation/anesthesia accident in the past; 2. Those who are known to be allergic to eggs, soy products, opioids and their remedies, propofol, etc., and those with contraindications to propofol, opioids and their remedies; 3. Participated in drug clinical trials as subjects within the past 3 months; 4. Pregnancy, lactation, possible pregnancy and planned pregnancy; 5. Other situations in which the investigator considers it inappropriate to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate of successful sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| induction time;emergency time;respiratory events;hypertension;hypotension;postoperative delirium;postoperative cognitive function;postoperative pain;peripheral circulation inflammatory index;postoperative nausea and vomiting;awareness during operation; | — |
Countries
China
Contacts
Public ContactZhong Jing
Fudan University Zhongshan Hospital
Outcome results
None listed