lung cancer
Conditions
Interventions
experimental group:opioids-free anesthesia management
control group:opioids anesthesia management
Sponsors
Zhongshan Hospital Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged above 18 years old and below 80 years old; 2. Preoperative diagnosis of lung tumor patients; 3. Undergo thoracoscopic surgery; 4. Good coagulation function, no anticoagulation therapy in the perioperative period, and epidural puncture can be accepted.
Exclusion criteria
Exclusion criteria: 1. Previous coronary heart disease, cerebral infarction, anemia, coagulation dysfunction; 2. Accept open surgery; 3. The patient cannot communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| chronic pain score 90 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Into PACU Steward Score;Out of PACU Steward Score;Delirium score 2 hours postoperatively; Incidence of nausea and vomiting;Incidence of itching;blood pressure;the dosage of esmolol;the dosage of esketamine;the dosage of fentanil;the dosage of ropivacaine;the dosage of rocuronium;the dosage of dexmedetomidine;chronic pain score 60 days after surgery;chronic pain score 30 days after surgery;the duration of the surgery;the duration of the anesthesia;the duration of the extubation;the dosage of phenylephrine;the dosage of ephedrine;the dosage of norepinephrine;fluid infusion in total;hemorrhage in total;urine volume;the extubation time after closed drainage of pleural cavity;oxygenation index before the surgery;oxygenation index after the surgery;IL-2 before the surgery;IL-2 one day after the surgery;IL-6 before the surgery;IL-6 one day after the surgery;IL-8 before the surgery;IL-8 one day after the surgery;IL-10 before the surgery;IL-10 one day after the surgery;TNF before the surgery;TNF one day after the surgery;anesthesia cost; | — |
Countries
China
Contacts
Public ContactWang Hao
Zhongshan Hospital, Fudan University
Outcome results
None listed