Bone health,physical growth, immune status
Conditions
Interventions
Interventional Group:Children formula milk powder,60g/d
Control Group:None or a 50gx2 bread per day
Sponsors
Inner Mongolia Yili Industrial Group Co., Ltd /Inner Mongolia Dairy Technology Research Institute Co., Ltd.
Eligibility
Sex/Gender
All
Age
4 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Age 4~6 years old; 2. There is no gender restriction; 3. Can normally enter kindergarten or primary school; 4. Willing to drink milk every day.
Exclusion criteria
Exclusion criteria: 1. Milk allergy, milk intolerance or people who are not used to drinking milk; 2. Those who have been diagnosed by the hospital with serious diseases such as heart, liver, kidney, brain, hematopoiesis, immunity, thyroid, and malignant tumors in the past 2 years, or who need to take medicine for more than 1 month; 3. Currently suffering from infectious diseases such as tuberculosis and hepatitis; 4. Take nutritional supplements such as active vitamin D3, calcium tablets or "nutrient packs"; 5. In the past 1 month, the average weekly frequency of drinking milk > 3 times (600ml); 6. Those with height growth value 8cm in the past year; 7. Do not sign the informed consent form, or other investigators deem it inappropriate for the participant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bone density;bone mineral content; | — |
Secondary
| Measure | Time frame |
|---|---|
| anthropometric indices;bone-specific alkaline phosphatase;osteocalcin;Blood ß-Glue Degradation Products;blood tartrate-resistant acid phosphatase;Immunoglobulin; | — |
Countries
China
Contacts
Public ContactChen Yuming
School of Public Health, Sun Yat-Sen University
Outcome results
None listed