cirrhosis
Conditions
Interventions
Control group:propofol
Sponsors
Zigong Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
19 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients between the ages of 19 and 75 years for the evaluation of portal hypertension; 2. ASA I-III; 3. Child-Turcotte-Pugh A, B; 4. Body mass index (BMI) >= 18 and = 10 and = 95% when breathing air; systolic (SBP) >= 90mmHg and = 60mmHg and = 55 and <= 100 beats/min; 6. Be able to understand the research process and methods, and voluntarily participate in this research.
Exclusion criteria
Exclusion criteria: 1. Patients with American Society of Anesthesiology (ASA) class IV or V physical condition; 2. Active gastrointestinal bleeding; 3. Continued drinking; 4. mental illness; 5. Drug abuse; 6. Patients taking neuroactive drugs (such as benzodiazepines, antiepileptic drugs, and any other sedatives and anesthetics); 7. Patients with clinical symptoms of hepatic encephalopathy; 8. Patients with visual or mental disorders who cannot complete the HE examination; 9. Those with contraindications to general anesthesia or those who have had a history of anesthesia accident in the past; 10. Known or suspected allergic or contraindicated to propofol injection, cyclopofol injection excipients, opioids, etc.; 11. Combined with craniocerebral loss, intracranial hypertension, stroke, unstable angina, myocardial infarction; 12. Those who have participated in any drug clinical trials within 1 month before screening; 13. Pregnant and lactating women; fertile women or men who are unwilling to use contraception throughout the trial period; subjects (including male subjects) who have a pregnancy plan within 1 month after the trial; 14. Subjects who are considered by the investigator to have any other factors that are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| psychometric tests; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function score;Stroop tests;critical flicker frequency;satisfaction survey;Hemodynamic parameters;The success rate of endoscopy diagnosis and treatment;side effect; | — |
Countries
China
Contacts
Public ContactChen Guanyu
Zigong Fourth People's Hospital
Outcome results
None listed