healthy volunteers
Conditions
Interventions
Soybean oil group:Replace daily cooking oil with soybean oil, the daily cooking oil is controlled at about 30g, and fat provides 30% daily energy.
Lard group:Replace daily cooking oil with lard, the daily cooking oil is controlled at about 30g, and fat provides 30% daily energy.
The group with oil blended by soybean oil and lard.:Replace daily cooking oil with oil blended by soybean oil and lard, the daily cooking oil is controlled at about 30g, and fat provides 30% daily ene
Sponsors
Institute of Nutrition and Health, Department of Medical College, Qingdao University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants are healthy and aged 18 to 63 years with a body mass index (BMI) (calculated as weight in kilograms divided by height in meters squared) of 16 to 40 kg/m2 were enrolled.
Exclusion criteria
Exclusion criteria: (1) reported history of CVD or severe diabetes or cancer; (2) allergy or intolerance to lard; (3) currently pregnant, or planning pregnancy; (4) particular nutritional habits such as vegetarianism; (5) participation in other research trials involving dietary or drug intervention in the past 3-months; (6) unable to comply with study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| free fatty acid;HDL-C;LDL-C;TC;body weight;height;waist circumference;triglyceride;glucose;insulin;GLP-1;glucogan;IL-1ß;IL-6;IL-8;IL-10;TNF-a;alanine aminotransferase;aspartate aminotransferase;g-glutaminyl transferase;alkaline phosphatase;lactate dehydrogenase;Uric Acid;urea;creatinine;gut microbiota;Urine metabolites;nitric oxide;total protein;albumin;globulin;total bilirubin;direct bilirubin;indirect bilirubin;albumin/globulin; | — |
Countries
China
Contacts
Public ContactLiu Zhiyuan
Qingdao University
Outcome results
None listed