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Short-term efficacy and safety of Callispheres drug-loaded microspheres chemoembolization for advanced breast cancer

Short-term efficacy and safety of Callispheres drug-loaded microspheres chemoembolization for advanced breast cancer

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051017
Enrollment
Unknown
Registered
2021-09-10
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

group 1:D-TACE

Sponsors

Suining Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Female patients aged 18-75 years; 2. Pathologically or histologically diagnosed patients with advanced clinical stage of primary breast cancer who are willing to downstage breast conserving patients, or patients who are inoperable and expected to be downstaged to be operable; 3. Patients who have no chance of surgery or resist surgical resection; 4. ECOG score 0-2, Child-Pugh class A or B; 5. Breast cancer patients who have not received other treatments within one month after initial diagnosis and progression; 6. Patients volunteered to participate in this trial.

Exclusion criteria

Exclusion criteria: 1. Pathological classification of patients who are not suitable for using epirubicin as a chemotherapy drug; 2. Patients with multiple organ malignant tumors; 3. People with mental illness and behavioral disorder; 4. Those who are allergic to contrast media; 5. Severe coagulation dysfunction (international normalized ratio exceeds or activated partial thromboplastin time exceeds the upper limit of normal by more than 2 times); 6. Serious infections that cannot be corrected after treatment; 7. Patients with severe cardiopulmonary insufficiency who cannot tolerate the operation; 8. Those with cachexia or multiple organ failure; 9. Pregnant or lactating women; 10. The investigator believes that any situation that will interfere with the evaluation of the efficacy of the trial, or interfere with the safety of the subjects, or interfere with the results of the trial; 11. Subjects deemed unsuitable by the investigator to be treated with this regimen.

Design outcomes

Primary

MeasureTime frame
objective response rate;disease control rate;

Countries

China

Contacts

Public ContactQin Wei

Suining Central Hospital

snDSA@163.com+86 18008258611

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026