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A clinical study on the effect of a novel non-opioid drug esketamine on pain and rapid recovery after thoracic surgery under total intravenous anesthesia

A clinical study on the effect of a novel non-opioid drug esketamine on pain and rapid recovery after thoracic surgery under total intravenous anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051000
Enrollment
Unknown
Registered
2021-09-10
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1:Intravenous use of esketamine
Group 2:Intravenous use of sufentanil

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 30 to 70 years (including 30 and 70 years old); 2. American society of anesthesiologists (ASA) classification I, II; 3. Elective patients undergoing thoracoscopic lung surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Abnormal liver and kidney function before surgery (preoperative liver enzyme index or creatinine exceeds 1.5 times the upper limit of normal); 2. Heart failure, arrhythmia; 3. Morbid obesity; 4. Bronchial asthma, abnormal coagulation function, history of cerebrovascular accident, increased intracranial pressure, intracranial space-occupying lesions; 5. Patients who have been dependent on or allergic to analgesics and anesthetics in the past; 6. Those who cannot cooperate due to various reasons.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;

Countries

China

Contacts

Public ContactZhou Hai

Xuzhou Central Hospital

zhouhai339339@163.com+86 18952171368

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026