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Correlation between molecular typing/immunotyping and clinical treatment of recurrent bladder cancer based on RNAseq

Correlation between molecular typing/immunotyping and clinical treatment of recurrent bladder cancer based on RNAseq

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050996
Enrollment
Unknown
Registered
2021-09-10
Start date
2022-01-08
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer

Interventions

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Sponsors

Tongji Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The enrolled patients are patients with recurrent bladder cancer, and can obtain tissue samples and clinical relevant data that meet the needs of the trial, including but not limited to basic patient information, pathological information, imaging data, treatment information, and other follow-up information. 2. Bladder cancer confirmed by pathology, and a pathological report is retained; recurrence needs to be determined by imaging evaluation. 3. The sampled tumor tissue samples can meet the minimum sequencing requirements (at least 50mg for fresh surgical tissue, at least 2 for fresh puncture tissue; at least 10 FFPE white films for surgical samples, for FFPE white sheets made from puncture samples, at least 15 sheets are required), and the homogeneous quality control is qualified. 4. Complete clinical follow-up information before treatment and within 2 years after treatment.

Exclusion criteria

Exclusion criteria: 1. Participate in other research and affect the observation of this research; 2. The patient refuses to sign the informed consent; 3. The researcher believes that the subjects are not suitable for high-risk diseases or other special circumstances to participate in the clinical trial.

Design outcomes

Primary

MeasureTime frame
RNA-seq;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactLuo Huarong

Tongji Hospital Affiliated to Tongji University

huarongluo8@sina.com+86 13671731421

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026