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Study on the effect of hypoxic cardiopulmonary exercise test on the evaluation of cardiac function in stroke patients

Study on the effect of hypoxic cardiopulmonary exercise test on the evaluation of cardiac function in stroke patients

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050995
Enrollment
Unknown
Registered
2021-09-10
Start date
2021-09-20
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart function decline after stroke

Interventions

Gold Standard:peak oxygen consumption (During CPET Exercise)
Index test:Peak&#32
consumption&#32
in&#32
hypoxic&#32
condition

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Stroke group: (1) Clinical reference was made to the ''Clinical Neurological Defect Degree Scoring Standards for Stroke Patients'' passed by the Fourth National Cerebrovascular Disease Academic Conference, the ICD-10 disease code of stroke confirmed by CT is I60, I61, I63 or I64, and the disease is stable; (2) Within 6 months of the disease course; (3) Aged 18-65 years; (4) It has the ability to change the posture of sitting and standing, and can use the sitting power car; (5) The score of the Simple Mental State Examination Scale>24, with the ability to understand the test steps and meaning; (6) Possess certain language communication skills and can communicate normally during the test; (7) Sign the informed consent. 2. Control group: (1) Good health and no cerebrovascular disease; (2) Aged 18-65 years; (3) It has the ability to change the posture of sitting and standing, and can use the sitting power car; (4) The score of the Simple Mental State Examination Scale>24, with the ability to understand the test steps and meaning; (5) Have certain language communication skills, and can communicate normally during the test; (6) Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Unstable vital signs, including resting state: respiratory rate >=35 times/min; SpO2=120 beats/min or =180mmHg or =110mmHg; body temperature >=38.5? or =200U/L, or aspartate aminotransferase AST>=200U/L; 5. Patients with other serious diseases, such as malignant tumors, end-stage chronic kidney disease, mental disorders, severe malnutrition, uncontrolled metabolic diseases such as diabetes, pulmonary embolism, severe lung diseases (asthma, COPD), etc.; 6. Those with unhealed lower extremity fractures and severe osteoporosis; those with high muscle tension and Ashworth grade 2-4; 7. Peripheral vascular disease restricting exercise; 8. Patients with severe mental disorders; 9. Pregnant or lactating patients; 10. Participated in other clinical trials of drugs or medical devices during the same period.

Design outcomes

Primary

MeasureTime frame
peak oxygen consumption;

Secondary

MeasureTime frame
minute ventilation volume;ventilatory equivalent for carbon dioxide;

Countries

China

Contacts

Public ContactXiong Feng

Shenzhen Second People's Hospital

252317913@qq.com+86 18782115004

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026