Obesity
Conditions
Interventions
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
Male
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who intend to undergo bariatric surgery and have no contraindications to surgery. 2. Body mass index (BMI) >=32.5kg/m^2 or 27.5= 11.1mmol/L; 2) Fasting blood glucose >= 7.0mmol/L; 3) Fasting blood glucose = 11.1mmol/L 2 hours after meals; 4) Glycated hemoglobin >= 6.5%; (3) Metabolic syndrome (IDF) includes: high triglyceride (fasting TG >= 1.7mmol/L), high density lipoprotein cholesterol (HDL-ch = 130mmHg or diastolic blood pressure >= 85mmHg); (4) Obesity-related comorbidities include abnormal glucose metabolism and insulin resistance, obstructive sleep apnea syndrome (OHSAS), nonalcoholic steatohepatitis, abnormal endocrine function, hyperuricemia, male sexual dysfunction, polycystic ovary syndrome, deformed arthritis, abnormal renal function, etc. 3. Male patients, aged 16-65 years. 4. Voluntarily sign the informed consent form and cooperate to complete the entire experiment.
Exclusion criteria
Exclusion criteria: 1. Secondary obesity caused by diseases that cause changes in growth hormone, adrenal cortex hormone, and thyroxine, such as acromegaly, Cushing's disease, hypothyroidism, etc. 2. Have a contagious skin or venereal disease, or have a rash or infected lesions in the area around the penis. 3. Those with intellectual disability or immaturity who cannot control their behaviors. 4. Severe coagulation disorder, or severe heart, brain, lung, liver, kidney and other diseases, uncontrolled hypertension (>= 150/100mmHg), symptomatic ischemic heart disease, cerebral infarction or obliterative arteriosclerosis, malignant tumor, poor general condition, difficult to tolerate general anesthesia and/or intolerable surgery. 5. Suffering from severe mental disorders (depression, schizophrenia, epilepsy) or long-term use of antipsychotic drugs. 6. There are congenital malformations and anatomical abnormalities of the genitals that obviously impair penile erection, or related diseases that cause organic erectile dysfunction, pelvic fractures, urethral rupture, after pelvic surgery (prostate, bladder, rectum), spinal trauma or surgery. 7. Have taken PDE5 inhibitor drugs for the first time within 1 week before screening, such as tadalafil, sildenafil, etc. 8. The investigator believes that there may be other circumstances that may increase the risk of subjects or interfere with the execution of clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hardness Vitality Units for Best Events; | — |
Secondary
| Measure | Time frame |
|---|---|
| IIEF-5;Erectile Rigidity;Erectile Duration;Tumescence Activity Units; | — |
Countries
China
Contacts
Public ContactMao Shanhua
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed