biliary atresia
Conditions
Interventions
control group:Conventional therapy
experimental group:Conventional therapy+Folic acid
Sponsors
Guangzhou Women and Children Medical Center
Eligibility
Sex/Gender
All
Age
No minimum to 2 Years
Inclusion criteria
Inclusion criteria: Two groups of participants will be recruited. 1.Patients diagnosed of highly suspected BA by experienced senior doctors. Inclusion criteria for this group: (1) Aged 0-90 days infants; (2) Cholangiography confirm biliary atresia; (3) Written informed consent from guardians; (4) Not accompanied by nervous system diseases such as epilepsy; (5) Without unexplained anemia; (6) Regular follow-up; 2. Post-Kasai Patients regular follow-up ongoing. Inclusion criteria for the second group: (1) 1-12months patients with BA; (2) Undergone surgery; (3) Written informed consent form guardians. (4) Without unexplained anemia; (5) Not accompanied by nervous system diseases such as epilepsy; (6) Without unexplained anemia; (7) Regular follow-up.
Exclusion criteria
Exclusion criteria: 1.Complications: Systemic inflammatory response syndrome or Multisystem malformation; 2.Unclear diagnosis of primary disease; 3.Unable to obtain parental authorization. 4.No operation was performed. 5.Unable to follow up in time. 6.Pernicious anemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver function indexes;Plasam folid acid level;iron level;microbiome; | — |
Countries
China
Contacts
Public ContactZhang Yuxia
Guangzhou Women and Children Medical Center
Outcome results
None listed