Gynecologic endoscopic surgery
Conditions
Interventions
DS group:opioid
DT group:Weak opioid
DE group: opioid free
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
19 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) grades I-III; 2. Aged 19 to 65 years; able to use PCA pump proficiently; 3. Understand and fully cooperate with the use of postoperative scoring tools.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI) > 30kg/m^2; 2. History of angina pectoris or myocardial infarction within the past 6 months; 3. Patients with poorly controlled or untreated hypertension (resting systolic/diastolic blood pressure >180/100mmHg); 4. Untreated or insufficiently treated patients with hyperthyroidism; 5. Patients with liver and kidney insufficiency; 6. Neuropsychiatric patients; 7. Long-term alcoholics; 8. Long-term use of sedative, hypnotic and analgesic drugs; 9. Heart rate < 50 beats/min or third degree atrioventricular block; 10. Known to be allergic to test drugs such as dexmedetomidine or/and esketamine; 11. Those who change the surgical method during the operation; 12. Loss of patient data during the perioperative period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ponv;pain;Ramsay??;MMSE??; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative amount of analgesic medication used, total number of analgesic pump presses, additional medication after pain is still felt;vital signs;Other adverse reactions;Perioperative data (drug use, duration of operation, duration of anesthesia, recovery time, extubation time, time to discharge, etc.; | — |
Countries
China
Contacts
Public ContactLi Xiaoxia
The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed