Skip to content

Effects of sub-anesthetic dose of esketamine on pain and early depression after cesarean section in women with different personalities

Effects of sub-anesthetic dose of esketamine on pain and early depression after cesarean section in women with different personalities

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050976
Enrollment
Unknown
Registered
2021-09-09
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum depression

Interventions

Experimental group:Intraoperative subanesthetic dose of esketamine was given intravenously
Control group:Intraoperative intravenous injection of the same amount of normal saline

Sponsors

Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women undergoing cesarean section under subarachnoid block at an elective schedule, singleton, and the gestation period is not less than 37 weeks; 2. Aged 18 to 40 years; 3. BMI 18.5-25; 4. ASA classification I or II.

Exclusion criteria

Exclusion criteria: 1. The patient refuses to sign the consent form for any reason; 2. There are contraindications for nerve block and intraspinal block, such as abnormal coagulation function and blood system related diseases; 3. History of opioid abuse or tolerance and related drug allergy, recent use of antipsychotic drugs, alcohol abuse or drug abuse; 4. Patients with language communication impairment or hearing impairment; 5. Dangerous placenta previa, intrauterine distress, intrauterine infection, stillbirth, etc.; 6. Severe cardiopulmonary disease or severe liver and kidney insufficiency; 7. Patients who refuse to use intravenous analgesia pump before surgery.

Design outcomes

Primary

MeasureTime frame
postpartum depression;NRS pain score;

Countries

China

Contacts

Public ContactWang Xiaobin

Affiliated Hospital of Southwest Medical University

wangxiaobin67@163.com+86 13708280087

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026