Obesity
Conditions
Interventions
Experimental group:Meal replacement + nutritionist enhanced dietary guidance
Sponsors
The First Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years, no gender limit; 2. BMI>=28kg/m^2; 3. Stable weight, 3-month weight loss <=2.5kg; 4. Patients agree to voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Liver function Child-Pugh score >= 7 points, that is, patients with moderate to severe liver function abnormalities; 2. Patients with chronic kidney disease; 3. History of malignant tumor; 4. History of severe cardiovascular or cerebrovascular disease (angina pectoris, myocardial infarction or stroke) within the past 6 months; 5. Diagnosed with gastrointestinal tumors, inflammatory bowel disease, irritable bowel syndrome and other serious gastrointestinal diseases or a history of gastrointestinal surgery within the past 12 months; 6. Pregnant and lactating patients, or patients planning to conceive within six months; 7. Participate in an intensive exercise training program (more than 210 minutes of moderate to high intensity training per week) or plan to start a new exercise program during the study period; 8. Taking prescription drugs for weight loss in the past 6 months; 9. In addition to the above criteria, the trial was determined in the judgment of the investigator to be unsafe or unsuitable for potential participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body mass index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition;Inflammatory markers;Safety index;Eating habits and living habits;Adverse reactions;Shedding rate;Compliance;European Five-Dimensional Health Scale; | — |
Countries
China
Contacts
Public ContactSui Yi
Outcome results
None listed