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Study on the expression level of GSNO in intestinal glial cells of patients with ulcerative colitis

Study on the expression level of GSNO in intestinal glial cells of patients with ulcerative colitis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050949
Enrollment
Unknown
Registered
2021-09-08
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis (UC)

Interventions

UC patient group:None
Healthy control group:None

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of ulcerative colitis, confirmed by histopathology and colonoscopy; 2. Patients with healthy physical examination or re-examination after endoscopic resection of colonic polyps and without symptoms of constipation/diarrhea were selected as the control group; 3. Accept colonoscopy; 4. Preoperative liver and kidney function, blood routine and cardiopulmonary function tests were normal, and there were no contraindications for colonoscopy; 5. Patients voluntarily participated in this study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiac, pulmonary and cerebrovascular diseases before surgery are contraindicated; 2. Serious infection; 3. History of mental illness that is not easy to control; 4. Colon tumors were found in endoscopy; 5. Gastrointestinal bleeding; 6. Combined with other intestinal diseases such as IBS.

Design outcomes

Primary

MeasureTime frame
Nitrosoglutathione;Nitrosoglutathione reductase;Nitric oxide;

Countries

China

Contacts

Public ContactYu Yanbo
yuyanbo2000@126.com+86 13658610919

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026