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Clinical study of rhubarb combined with transcutaneous electrical stimulation in improving acute gastrointestinal injury in patients with sepsis

Clinical study of rhubarb combined with transcutaneous electrical stimulation in improving acute gastrointestinal injury in patients with sepsis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050940
Enrollment
Unknown
Registered
2021-09-08
Start date
2021-09-10
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Group 2:Percutaneous electrical stimulation
Group 3:Transcutaneous electrical stimulation + rhubarb treatment

Sponsors

Affiliated Hospital of Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged > 18 and < 80 years; 2. Patients admitted to ICU; 3. Meet the diagnostic criteria of sepsis 3.0; 4. Meet the diagnostic criteria of AGI, and be graded as I, II, and III; 5. The patient or the patient's family signed the informed consent and cooperated with the investigation and complied with the patient well.

Exclusion criteria

Exclusion criteria: 1. Those with contraindications to enteral nutrition such as gastrointestinal perforation, intestinal obstruction, gastrointestinal surgery and intestinal fistula; 2. Those with skin infections, ulcers and scars should not undergo acupoint electrical stimulation therapy; 3. The disease is endangered and the expected survival time is less than 5 days; 4. Patients with impaired immune function or undergoing immunotherapy; 5. Pregnant patients; 6. Those who are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Regular bowel sounds recovery time;Antral motility index;Time for enteral nutrition to reach standard;Enteral nutrition reached the standard on day 7;

Secondary

MeasureTime frame
Inflammation levels;Infection index;Intestinal mucosal permeability index;Gastrointestinal motility index;The immune indexes;Nutrition indicators;Prognostic indicators;

Countries

China

Contacts

Public ContactYin Jiangtao

Affiliated Hospital of Jiangsu University

doctoryjt2438@163.com+86 13952943135

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026