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Brain network mechanism of acupuncture combined with opioids in the treatment of cancer pain based on a practical randomized controlled trial

Brain network mechanism of acupuncture combined with opioids in the treatment of cancer pain based on a practical randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050935
Enrollment
Unknown
Registered
2021-09-08
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer pain

Interventions

Fake needle group:sham acupuncture
Waiting group:analgesic management

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. At least 18 years old; 2. Pathological diagnosis of malignant tumor; 3. Moderate or severe cancer pain on admission (Numerical Rating Scale, NRS>=4); 4. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating patients; 2. Contraindications of acupuncture (such as abnormal blood coagulation test, burns, eczema, ulcers, frostbite ulcers and other local skin lesions); 3. Contraindications for MRI scanning; 4. Brain tumor, cancer brain metastases or other space-occupying lesions in the brain; 5. Serious complications (such as severe arrhythmia, myocardial infarction or neutropenia); 6. Unable to agree to, cooperate with treatment or evaluation.

Design outcomes

Primary

MeasureTime frame
Edmonton Symptom Assessment System;

Secondary

MeasureTime frame
Opioid dosages;Number and frequency of outbreak pain;Laboratory indicators;Specific changes in brain function network;

Countries

China

Contacts

Public ContactHe Yihan

Guangdong Provincial Hospital of Chinese Medicine

yihanhe@gzucm.edu.cn+86 15013105897

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026