mild cognitive impairment
Conditions
Interventions
Intermittent hypoxia training group:Routine rehabilitation intervention combined with Intermittent inhalation of 10-15% oxygen
TMS group:Routine rehabilitation intervention combined with TMS
High-intensity interval group:Routine rehabilitation intervention combined with high intensity interval training
Sponsors
Shanghai University of Medicine&Health Sciences
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 55 years and above; 2. Informed consent; 3. Have good understanding and communication skills.
Exclusion criteria
Exclusion criteria: 1. Physically disabled and unable to complete the relevant functional assessment; 2. Cannot stand or perform body composition testing with pacemakers and stents, or use metal or electrical implants (eg, deep brain stimulators, ventriculoperitoneal shunts, aneurysm clips, pacemakers, cochlea, surgical staples on the scalp); 3. Have other acute or chronic diseases that will affect physical activity; 4. Those who have severe systemic diseases such as cardiopulmonary disease and cannot tolerate it; 5. Those with a family history of mental illness, depression or epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function;balance capability;executive function;motor function;EEG;cerebral oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life;depression;anxiety;sleep quality;health condition;four blood lipids;blood glucose;C-reactive protein;arterial hardness;insulin sensitivity index;HbA1C;body composition;complete blood count;homocysteine;advanced glycation end products;cerebral blood flow; | — |
Countries
China
Contacts
Public ContactCai Ming
Shanghai University of Medicine & Health Sciences
Outcome results
None listed