Knee osteoarthritis
Conditions
Interventions
groupA:200mg celecoxib (200mg qd po)
groupB:200mg celecoxib (200mg qd po)
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients who meet the KOA diagnostic criteria of Osteoarthritis Diagnosis and Treatment Guidelines (2018 edition) issued by the Joint Surgery Group of The Orthopaedic Society of the Chinese Medical Association; 2.Aged 40 to 70 years, including 40 and 70 years, male or female. 3.KL classification <= grade 3; 4.Patients who have a mobile phone and can use the application proficiently; 5.Patients who understand Chinese language and can complete the WOMAC index independently; 6.Patients who have signed the informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with acute meniscus injury, peripheral ligament rupture injury, rheumatic arthritis, rheumatoid arthritis, peripheral tumor of knee joint, tuberculosis, idiopathic osteonecrosis of the knee; 2.Patients with serious cardiovascular, lung, liver, kidney and hematopoietic diseases, hemophilia and other hemorrhagic diseases, mental illness, pregnancy and lactation; 3.Patients who are allergic or intolerant to trial medication; 4.Patients who had received other treatments in the last 2 months has an effect on the study; 5.Patients are not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC score; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC Pain subscale score;WOMAC Stiffness subscale score;WOMAC Physical Function subscale score; | — |
Countries
China
Contacts
Public ContactYuan Wei’an
Outcome results
None listed