Cardiopulmonary failure
Conditions
Interventions
Traditional sedation group:Midazolam/Propofol
Comfortable sedation group:Dexmedetomidine combined with sedation titration
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with severe and reversible cardiopulmonary failure requiring ECMO support; 2. Aged 18-75 years; 3. Patients or their entrusted agent sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Heparin-induced thrombocytopenia (HIT); 2. Patients who have been confirmed or suspected to be accompanied by nerve injury; 3. Pregnant patients, Alzheimer's disease, or psychiatric diseases; 4. Serious primary diseases affecting survival: multiple unresectable malignant tumors, blood diseases and HIV, etc.; 5. Burns, drug overdose or poisoning, acute liver failure; 6. The need for continuous use of neuromuscular blocking agents; 7. Patients who have been determined by the competent doctor to be unsuitable for inclusion in the group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Richmond agitation sedation scale;Cumulative amount of sedative and analgesic drugs used; | — |
Countries
China
Contacts
Public ContactGuo Haipeng
Qilu Hospital of Shandong University
Outcome results
None listed