diminished ovarian reserve (DOR)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-40 years. 2. Decreased ovarian reserve: AMH 3.6; or the sum of bilateral basal antral follicle counts (AFC) is less than 7; or there has been a history of low ovarian response to IVF in the past, manifested as the number of oocytes retrieved in the last ovulation cycle < 3; any two of the above conditions are met. 3. Voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Chromosomal abnormalities; 2. There has been a history of ovarian surgery, such as ovarian surgery due to ovarian teratoma or ovarian chocolate cyst; 3. Suffering from other endocrine diseases such as thyroid disease, hyperprolactinemia, diabetes, adrenal disease, etc.; 4. Suffering from clearly diagnosed autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, etc.; 5. Patients with a history of malignant tumors who have received radiotherapy and chemotherapy in the past; 6. Received acupuncture and moxibustion treatment in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian reserve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood prolactin and testosterone levels;Oxidative stress related indicators;Egg shape;Fertilization rate;Embryo status; | — |
Countries
China
Contacts
Huazhong University of Science Tongji Hospital, Tongji Medical College