Correlation between morphological abnormalities of meibomian gland and blepharoester in confocal microscope

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050900

Enrollment

Unknown

Registered

2021-09-07

Start date

2021-10-07

Completion date

Unknown

Last updated

2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meibomian gland dysfunction

Interventions

Solid meibum group:No

Liquid meibum group:No

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with meibomian gland dysfunction with complaints of eye dryness, foreign body sensation, burning sensation, eye fatigue, acid distension, redness of eyes, visual blur, and finally meibomian gland massage showed that the meibomian gland ester was solid or liquid.

Exclusion criteria

Exclusion criteria: 1. Wearing corneal contact lens; 2. Patients with history of ocular trauma (acid and alkali burns); 3. The recent history of eye surgery; 4. Congenital abnormal meibomian gland morphology and patients with dysplasia; 5. The eye tattoo history; 6. Immune system diseases, such as sjogren's syndrome patients; 7. Long before the meibomian gland massage or fumigation treatment, long-term use of hormone drugs; 8. Involuntary researchers involved in the project.

Design outcomes

Primary

Measure	Time frame
Diameter of meibomian gland opening;Area of meibomian gland opening;Maximum diameter of meibomian gland acinus;Minimum diameter of meibomian gland acinus;Meibomian gland acinar area;	—

Countries

China

Contacts

Public ContactWang Ting

Eye Hospital of Shandong First Medical University

wt-ting@163.com+86 13869182795

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026