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Comparison of clinical outcomes of D4 and D5 selective single embryo transfer in IVF/ICSI: a single center, prospective, randomized controlled clinical study

Comparison of clinical outcomes of D4 and D5 selective single embryo transfer in IVF/ICSI: a single center, prospective, randomized controlled clinical study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050899
Enrollment
Unknown
Registered
2021-09-07
Start date
2021-08-31
Completion date
Unknown
Last updated
2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sterility

Interventions

Group D4:D3 embryos were cultured for one day
Group D5:D3 embryos were cultured for 2 days

Sponsors

The Sixth Affiliated Hospital of Guangzhou Medical University (Qingyuan People's Hospital)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 34 Years

Inclusion criteria

Inclusion criteria: 1. Aged = 1.1 ng/ml ; 3. The first fresh IVF/ICSI cycle; and the antagonist regimen or down regulation protocol was used; 4. D3 has >= 4 high-quality cleavage embryos; 5. Endometrial thickness on HCG day >= 8 mm; 6. E2 level < 4000 pg/ml on HCG day.

Exclusion criteria

Exclusion criteria: 1. Chromosome abnormality; 2. Diabetes, thyroid disease, adrenal gland and other rheumatic immune diseases; 3. Uterine lesions (hysteromyoma, endometriosis, endometrial polyps, intrauterine adhesion, intrauterine effusion, etc.); 4. Hydrosalpinx; 5. Repeated implant failure or recurrent abortion.

Design outcomes

Primary

MeasureTime frame
Preterm birth rate;

Secondary

MeasureTime frame
Live birth rate;Embryo implantation rate;Clinical pregnancy rate;Abortion rate;Ongoing pregnancy rate;Ectopic pregnancy rate;Multiple birth rate;

Countries

China

Contacts

Public ContactChen Cairong

The Sixth Affiliated Hospital of Guangzhou Medical University (Qingyuan People's Hospital)

cairong1222@163.com+86 13927681331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026