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Randomized controlled clinical trial of recombinant human erythropoietin injection once a week and divided times in the treatment of renal anemia in maintenance hemodialysis patients

Randomized controlled clinical trial of recombinant human erythropoietin injection once a week and divided times in the treatment of renal anemia in maintenance hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050894
Enrollment
Unknown
Registered
2021-09-07
Start date
2019-07-22
Completion date
Unknown
Last updated
2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis complicated with renal anemia

Interventions

experimental group:According to the Hb level before the study and the use of recombinant human erythropoietin injection, they were divided into two groups: 1. Recombinant human erythropoietin injectio
2. 4000 IU / time, once a week, intravenous injection&#32
control group:According to the Hb level before the study and the use of recombinant human erythropoietin injection, they were divided into two groups: 1. Recombinant human erythropoietin injection 200
2. 2000iu / time, 1 branch / time,&

Sponsors

Tongzhou District, Dongzhimen Hospital, Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
32 Years to 78 Years

Inclusion criteria

Inclusion criteria: 1. 100 = 100ng / ml and transferrin saturation >= 10%; 6. Voluntary subjects, patients who have signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with uncontrolled severe hypertension (SP >= 180mmhg, DP >= 110mmhg); 2. Patients with congestive heart failure [New York Heart Association cardiac function grade III or above]; 3. Ast or ALT value > 3 times the upper limit of standard value and ALB 15mg / L 4 weeks before enrollment; 5. Positive occult blood in stool 4 weeks before enrollment; 6. Patients who had undergone surgery with massive bleeding within 3 months before enrollment or who planned to undergo surgery during the clinical trial (except arteriovenous shunt); 7. Patients with malignant tumors (including hematological malignancies), hematological diseases (myelodysplastic syndrome, hemolytic anemia, etc.) or obvious hemorrhagic diseases; 8. Those who have received protein assimilation hormone, testosterone heptanate or methandrone within 3 months; 9. Previous functional organ transplantation or scheduled organ transplantation or no kidney; 10. Past alcohol and drug abusers; 11. Those who are unable to cooperate or unwilling to cooperate due to neurological and mental diseases; 12. Thos e who are allergic to known ingredients of test drug or control drug and allergic constitution or ESAs resistance; 13. Pregnant or lactating women or those with recent birth planning; 14. A history of blood transfusion within 3 months; 15. Participated in other clinical trials in recent 3 months; 16. The researcher believes that there are any other medical conditions that are not suitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
hemoglobin;

Countries

China

Contacts

Public ContactLI JIanjun

Tongzhou District, Dongzhimen Hospital, Beijing University of Chinese Medicine

15810594665@126.com+86 15810594665

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026