Sudden deafness
Conditions
Interventions
Round window membrane drug delivery group:Round window membrane drug delivery
Microcirculation drug group:Microcirculation-improving drugs oral taken for one month
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years; 2. Patients with total deafness diagnosed according to the 2015 guidelines; 3. After 5-7 days of conservative treatment according to the 2015 guidelines, hearing at impaired frequency increased by less than 15 dB on average; 4. The subjects or their legal representatives can understand the purpose of the study, show their compliance with the study protocol, sign informed consent and cooperate with the visitors.
Exclusion criteria
Exclusion criteria: 1. Subjects with serious cardiovascular and cerebrovascular diseases or organ failure; 2. Subjects who have participated in clinical trials of any other drug or medical device within the last 3 months; 3. Subjects deemed unsuitable for the clinical trial by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pure tone audiometry(PTA); | — |
Countries
China
Contacts
Public ContactChen Zhengnong
Shanghai Sixth People's Hospital
Outcome results
None listed