Intrahepatic cholestasis of pregnancy
Conditions
Interventions
Intrahepatic cholestasis of pregnancy group:No
Control group:No
Sponsors
Chengdu Women's and Children's Central Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Experimental group: patients who were diagnosed as ICP for the first time after 14 weeks of gestation, had fasting blood total bile acid >= 10 umol/l, and had not been treated before; 2. Control group: patients who corresponded to the study group's gestational age without comorbidities and complications Pregnant women, without pregnancy complications and complications.
Exclusion criteria
Exclusion criteria: 1. People who have undergone major gastrointestinal surgery (cholecystectomy, appendectomy) and major intestinal resection within 5 years; 2. People who have hepatobiliary disease, inflammatory bowel disease, irritable bowel syndrome, autoimmune diseases; 3. People with hypertension during pregnancy, gestational diabetes or other pregnancy complications and medical complications; 4. People who have a history of mental illness and cannot cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora; | — |
Countries
China
Contacts
Public ContactYang Xiao
Chengdu Women's and Children's Central Hospital
Outcome results
None listed