Cognitive frailty
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed with CF; 2. Aged >= 60 years; 3. Had no regular physical exercise for at least half a year(regular exercise means exercise with a frequency of at least twice a week and at least 20 min per session); 4. Provided informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with hypertension with uncontrollable blood pressure (systolic blood pressure greater than 160 mmHg or diastolic blood pressure greater than 100 mmHg); 2. History of alcohol and drug abuse; 3. History of mental illness(including personality disorder,schizophrenia,etc),major depression(Beck Depression Scale > 10 points),severe aphasia and audio-visual disorders,severe organ failure,history of coronary artery disease,musculoskeletal disorders and other exercise contraindications; 4. Metal implants(including fixed mental dentures,pacemakers,etc) and other reasons making the patient unsuitable for MRI scans; 5. Participating in another clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive frailty;Static balance function;Dynamic balance function;Overall balance function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fall effectiveness evaluation;Grip strength;Elderly lower limb muscle strength; | — |
Countries
China
Contacts
Shanghai University of Medicine and Health Sciences