Influence of sevoflurane inhalation anesthesia versus propofol intravenous anesthesia on intraoperative neuromonitoring during thyroidectomy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050846

Enrollment

Unknown

Registered

2021-09-04

Start date

2021-09-13

Completion date

Unknown

Last updated

2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid tumor

Interventions

Sevoflurane group:Maintenance of anaesthesia with sevoflurane

Propofol group:Maintenance of anaesthesia with propofol

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing thyroidectomy used intraoperative neuromonitoring; 2. ASA classification I-II; 3. Aged 18-65 years; 4. Body mass index 19-28 kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Pregnant or breastfeeding; 2. Suffering from hypertension, cardiopulmonary insufficiency or cardiovascular disease; 3. Neuromuscular disease; 4. The presence of damage to the recurrent laryngeal nerve or vagus nerve; 5. Vocal cord dysfunction at the time of preoperative laryngoscopy; 6. Taking medication that may affect neuromuscular transmission; 7. Potential risk of airway difficulties; 8. Any contraindication to the anaesthetic agent used during the procedure; 9. History or family history of malignant hyperthermia; 10. Refusal to participate in the study.

Design outcomes

Primary

Measure	Time frame
V1, R1, R2, V2 of intraoperative neuromonitoring;	—

Secondary

Measure	Time frame
Intubation condition score;	—

Countries

China

Contacts

Public ContactDou Yunling

The First Affiliated Hospital of Sun Yat-Sen University

dou-yl@163.com+86 18688882811

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026