The effect of COMT polymorphism on fentanyl and dexmedetomidine in labor anxiety and analgesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050845

Enrollment

Unknown

Registered

2021-09-04

Start date

2018-01-01

Completion date

Unknown

Last updated

2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum anxiety and pain

Interventions

fentanyl group:Ropivacaine combined with fentanyl

dexmedetomidine group:Ropivacaine combined with dexmetomidine

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Natural delivery under painless delivery; 2. ASA grade I-II; 3. Aged 20-32 years; 4. Gestational weeks 38-41 weeks; 5. Voluntary participation in the trial.

Exclusion criteria

Exclusion criteria: 1. Singleton cephalic position and cephalopelvic disproportion; 2. Pathological obstetrics in prenatal examination; 3. Complicated with severe internal and surgical diseases; 4. History of alcoholism, smoking or psychiatric illness; 5. History of severe mental illness or long-term use of psychoactive substances; 6. Contraindications of epidural puncture.

Design outcomes

Primary

Measure	Time frame
Anxiety evaluation of maternity;Analgesia Score;	—

Countries

China

Contacts

Public ContactYing Zhang

Traditional Chinese Medicine Hospital of Southwest Medical University

zhangying021210@163.com+86 13551720908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026