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Effects of Ninjurin-1 and its potential mechanisms on the development of atherosclerosis

Effects of Ninjurin-1 and its potential mechanisms on the development of atherosclerosis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050838
Enrollment
Unknown
Registered
2021-09-04
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Asymptomatic carotid plaque formation group:No
Control group:No

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for stroke: (1) Aged >= 18 years; (2) Within 7 days of onset, CTA and CTP indicate that the core of infarction exists or the MR DWI sequence can be seen as an acute cerebral infarction lesions; 2. Inclusion criteria for the asymptomatic carotid plaque formation group: (1) Aged >= 18 years; (2) No history of ischemic stroke or TIA in the past; (3) Carotid artery plaque formation detected by carotid color Doppler ultrasound; 3.Inclusion criteria of the healthy control group: (1) Aged >= 18 years; (2) No history of ischemic stroke or TIA in the past; (3) Patients without carotid artery plaque in carotid artery color Doppler ultrasound examination.

Exclusion criteria

Exclusion criteria: 1. Severe cardiac insufficiency; 2. Severe renal insufficiency; 3. Severe infection; 4. Multiple sclerosis; 5. Rheumatic immune disease.

Design outcomes

Primary

MeasureTime frame
Ninjurin-1;

Secondary

MeasureTime frame
Matrix metalloproteinase 9 (MMP-9);

Countries

China

Contacts

Public ContactFang Qi

The First Affiliated Hospital of Soochow University

fangqi_008@126.com+86 15351852250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026