Kidney stone
Conditions
Interventions
Experimental group:No antibiotics before surgery
Control group:3 days of antibiotics before surgery
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years; 2. Negative preoperative urine culture; 3. White blood cells >= 10 /visual field, and/or nitrite positive under high magnification of preoperative urine sediment; 4. Serum creatinine < 133 umol/L; 5. ASA I/II; 6. Renal calculi 2-4 cm.
Exclusion criteria
Exclusion criteria: 1. Patients who had been treated with antibiotics within 4 weeks before operation (oral/intravenous); 2. Patients with fever within 2 weeks before operation; 3. Severe hydronephrosis or chronic urinary retention existed in the kidney; 4. Patients with ureteral calculi and bladder calculi; 5. Patients with abnormal lysis structure (isolated kidney, ectopic kidney, horseshoe kidney, repeated kidney), ureteral stricture and urinary diversion; 6. Ureteral stent implantation, renal fistula patients and indwelling catheter patients; 7. Patients with renal abscess found during operation; 8. Patients who underwent bilateral surgery or ipsilateral ureteral lithotripsy at the same time; 9. Patients with long-term immunosuppressive agents and glucocorticoids; 10. Patients with hypertension and diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of fever; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of systemic inflammatory response syndrome (SIRS);Duration of hospital stay;Duration of operation;Complications; | — |
Countries
China
Contacts
Public ContactZeng Guohua
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed