Bone defect
Conditions
Interventions
Experimental group:Absorbable artificial bone
Control group:Allogeneic bone implant materials
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years, male or female; 2. Patients who were clinically diagnosed as limb bone defects and needed bone defect repair; 3. Patients who voluntarily participate and sign informed consent and participate in clinical follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with mental disorders or unable to understand the requirements for participation in the study; 2. Subjects with poor expected compliance; 3. Known to have a history of allergy to one or more implant materials; 4. Patients with hemorrhagic diseases; 5. Patients with severe cardiopulmonary and other systemic diseases who the researchers believe cannot tolerate the operation; 6. Local or systemic active infection lesions; 7. Pregnant or lactating women; 8. Patients with long-term hormone use, mental illness, drug abuse or alcoholism; 9. Critical patients such as advanced tumors; 10. Fasting blood glucose was more than 8.0 mol/L in patients with diabetes mellitus; 11. Patients who have participated in clinical trials within 3 months; 12. The investigator believes that other reasons are not suitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone graft fusion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone defect healing rate ;Quality of life of subjects;Product performance evaluation; | — |
Countries
China
Contacts
Public ContactZhao Jinzhong
Shanghai Sixth People's Hospital
Outcome results
None listed