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A randomized controlled trial on the effectiveness and safety of acupuncture in the treatment of gastrointestinal dysfunction after chemotherapy for colorectal cancer

A randomized controlled trial on the effectiveness and safety of acupuncture in the treatment of gastrointestinal dysfunction after chemotherapy for colorectal cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050821
Enrollment
Unknown
Registered
2021-09-04
Start date
2021-08-30
Completion date
Unknown
Last updated
2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Acupuncture group:Acupuncture
Sham acupuncture group:Sham acupuncture

Sponsors

Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Males or females, aged 18 to 75 years; 2. Colonoscopy and histopathological biopsy diagnosed as primary colon cancer or primary high rectal cancer, staging I-III; 3. Have completed at least one cycle of chemotherapy and developing symptoms related to gastrointestinal dysfunction after chemotherapy, including nausea, vomiting, abdominal distension, diarrhea, constipation, etc.; any item in the gastrointestinal symptom grading scale was scored above 2 points; 4. The Karnofsky score >= 60 points, or the ECOG physical fitness score = 3 months; 5. No abdominal surgery history or more than 3 months after abdominal surgery; 6. Have not received acupuncture treatment and have not participated in other clinical studies within the past 3 months; 7. Gastrointestinal dysfunction caused by non-opioids or metabolic imbalances; 8. Sign the informed consent form and voluntarily participate in this study.

Exclusion criteria

Exclusion criteria: 1. Have undergone total colorectal resection or who have a fistula; 2. With severe heart disease, cerebrovascular disease; 3. Use warfarin, heparin, etc., or who have abnormal hematopoietic function; 4. Unconsciousness, unable to express subjective symptoms and mental illness; 5. Long-term use of laxatives, or taking drugs that affect gastrointestinal function and those who are bedridden for a long time.

Design outcomes

Primary

MeasureTime frame
Gastrointestinal symptom rating scale;

Secondary

MeasureTime frame
Evaluation of the Functional Assessment of Cancer Therapy-Colorectal (V4.0);SAS (Self-Rating Anxiety Scale);SDS (Self-Rating Depression Scale);

Countries

China

Contacts

Public ContactLiang Fanrong

Chengdu University of Traditional Chinese Medicine

acuresearch@126.com+86 13608058216

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026