Bell's palsy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years; 2. Meet the above diagnostic criteria for facial paralysis: H-B grade II-VI, the total score of Sunnybrook scale <= 89 (to be improved); 3. Acute stage: course <= 3 days; 4. Unilateral disease; 5. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Otitis media, mastoiditis, labyrinthitis, mumps and other concurrent peripheral facial paralysis; 2. Peripheral facial paralysis caused by posterior fossa lesions such as acoustic neuroma, skull base meningitis, intracranial metastasis of cancer, multiple sclerosis, etc.; 3. Central facial paralysis; 4. Patients with Hunter's syndrome; 5. Those who are complicated with serious cardiovascular and cerebrovascular diseases, diabetes, hypertension, serious primary diseases of liver, kidney, lung and blood system, malignant tumor, ulcer of digestive system and bleeding tendency and are expected to fail to complete the test; 6. Participants in other clinical trials within 1 month; 7. Glaucoma patients; 8. Pregnant or lactation women or allergic constitution; 9. Psychiatric patients with neurological, mental illness, illiteracy or poor compliance in the screening process who are not eligible to fill in the questionnaire.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diameter of facial nerve;Sunnybrook facial nerve grading; | — |
Secondary
| Measure | Time frame |
|---|---|
| Echo intensity and thickness of facial muscles;Blood flow parameters of facial artery;House-brackmann classification of facial nerve function;Routine blood;Serum cytokines (IL-6?IL-8?IL-10?TNF-alpha); | — |
Countries
China
Contacts
The First Affiliated Hospital of China Medical University