Type 2 diabetes
Conditions
Interventions
Non diabetic group:400ml 12.5% carbohydrates taken orally 2-3 hours before operation
Type 2 diabetes control group:400ml artificial sweetener solution taken orally 2 ~ 3 h before operation
Type 2 diabetes intervention group:400ml 12.5% carbohydrates taken orally 2 ~ 3 h before operation
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The patients were diagnosed as type 2 diabetes (preoperative fasting blood glucose control was < 7.1 mmol/l); 2. Colorectal cancer diagnosed by colonoscopy biopsy and CT examination showed that there was no distant metastasis and radical resection could be performed, and no anti colon cancer treatment such as radiotherapy and chemotherapy was performed before operation; 3. Aged 18 to 80 years, male and female, ASA grade II - III; 4. Voluntarily participate in the experiment and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, lung, brain and liver dysfunction; 2. Emergency or palliative surgery; 3. Coexisting diseases leading to impaired gastric emptying (intestinal obstruction, gastroesophageal reflux, esophageal hiatal hernia, history of chronic aspiration); 4. Those who may have difficulty in endotracheal intubation; 5. Those who received parenteral nutrition support before operation; 6. Elevated blood sugar caused by drugs; 7. Patients with unclear mind and consciousness after operation; 8. The operation time was longer than 6-8 h. Due to the problem of drug accumulation, the postoperative water intake time was appropriately prolonged; 9. Allergic to fructose or malt paste; 10. Those with communication or cognitive impairment, alcohol dependence and history of drug abuse; 11. Lactating and pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative insulin resistance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative blood glucose;Cancer prognosis;Gastric emptying 1 hour before operation;Perioperative patient comfort;Perioperative complications;The length of hospital stay; | — |
Countries
China
Contacts
Public ContactLyu Feng
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed