Chronic constipation
Conditions
Interventions
case series:No
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years, gender is not limited; 2. Patients with symptoms for at least 3 months before diagnosis, with any one of the following main complaints: defecation feels laborious; defecation is dry ball feces or hard feces (Bristol stool character scale type 1-2); defecation is incomplete; Defecation has anorectal obstruction/blockage; defecation requires manual assistance (eg, finger-assisted defecation, pelvic floor support) spontaneous defecation less than 3 times per week; 3. Able and willing to comply with the taboos and restrictions specified in the program; 4. Subjects must be willing and able to fill out questionnaires and diaries; 5. Subjects can be followed up within the trial period in accordance with the provisions of the trial protocol; 6. Subjects agree to take contraceptive measures during the study; 7. The subjects understand the purpose and procedures of the trial and voluntarily participate in the trial, and voluntarily sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to barium; 2. Known or suspected organic lesions of the large intestine, namely obstruction, cancer or inflammatory disease; 3. Known or suspected stenosis, obstruction, diverticulum, perforation, bleeding, infection of the digestive tract; 4. Women of childbearing age have positive blood pregnancy test at screening time; 5. Women who are pregnant or breastfeeding; 6. Participated in other interventional clinical trials in the last 3 months; 7. Other conditions that the investigator determines the subjects are not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Excretion rate of radiopaque markers;Colonic transit time in people with chronic constipation; | — |
Countries
China
Contacts
Public ContactHou Xiaohua
Huazhong University of Science and Technology
Outcome results
None listed