Osteoarthritis of the hip or knee, necrosis of femoral head
Conditions
Interventions
Group A:Those who have a history of oral insulin sensitizing drugs before admission and persist in taking them within 1 month before surgery
Group B:There is no history of oral insulin sensitization drugs before admission, and those who insist on oral administration of other types of hypoglycemic drugs
Group C:No history of oral hypoglycemic drugs before admission, poor blood glucose control after admission
Sponsors
Department of Orthopedics, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Diagnosed as osteoarthritis, femoral head necrosis, DDH (type I/II) for initial unilateral THA or TKA; 2.Diagnosed as diabetes; 3.BMI > 18.5.
Exclusion criteria
Exclusion criteria: 1.History of previous surgery, trauma, chronic infection of the ipsilateral joint; 2.Severe heart and lung disease, gastrointestinal disease, liver and kidney dysfunction, rheumatoid immune system diseases such as rheumatoid disease, and psychiatric history; 3.Type 1 diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fasting blood sugar;C reactive protein;IL-6;IL-6;hemoglobin;Hematocrit;Neutrophils/lymphocytes;albumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| serum potassium;insulin dosage;morphine use;operation time;hospital stay;complications; | — |
Countries
China
Contacts
Public ContactKang Pengde
West China Hospital, Sichuan University
Outcome results
None listed