Effect of dexmedetomidine epidural infusion on the quality of early postoperative recovery in elderly patients undergoing laparoscopic radical colorectal cancer surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050780

Enrollment

Unknown

Registered

2021-09-04

Start date

2021-09-02

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Dexmedetomidine + ropivacaine group:The L1~L2 intervertebral space was selected for epidural puncture catheterization, and dexmedetomidine (0.5µg/ml) + ropivacaine (0.125%) was given epidurally in a l

ropivacaine group:Epidural puncture catheterization was the same as in the DR group, and epidural ropivacaine (0.125%) was given in a loading volume of 10 ml followed by continuous pumping at 5 ml/h u

Eligibility

Sex/Gender

All

Age

65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Above the age of 65 years; 2. Patients undergoing elective laparoscopic radical resection of colorectal cancer; 3. ASA classification I~III; 4. Agree to join the group and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Abnormal platelets and coagulation; 2. Local anesthetic allergy; 3. Epidural anesthesia is contraindicated; 4. Epidural catheter failure; 5. The blocking plane is not satisfied; 6. Conversion to laparotomy, intraoperative hemorrhage occurred.

Design outcomes

Primary

Measure	Time frame
The Quality of Recovery-15 score;Delirium assessment;	—

Countries

China

Contacts

Public ContactLi Yang

Shaanxi Provincial People's Hospital

li_yang1971@126.com+86 18629335732

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026