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Clinical experimental study plan for adult pulp regeneration based on collagen 3D stent compound concentrated growth factor (CGF)

Clinical experimental study plan for adult pulp regeneration based on collagen 3D stent compound concentrated growth factor (CGF)

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050776
Enrollment
Unknown
Registered
2021-09-04
Start date
2021-09-10
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpitis or periapical disease

Interventions

Group 1:CGF
Group 2:CGF+ collagen 3D stent

Sponsors

The Third Affiliated Hospital of The Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 65; 2. All the teeth except the third molars (the roots have been fully developed) have symptoms of irreversible pulpitis or periapical periodontitis. X-rays show normal periapical period, widened periapical membranous cavity or apical shadow.

Exclusion criteria

Exclusion criteria: 1. The tooth has root fracture; the tooth cannot be directly repaired with resin; the large area of the tooth is damaged, which makes it difficult to check the pulp vitality in the future; 2. The tooth is missing more than 2mm below the gum; the depth of the periodontal pocket is more than 3mm; there is no opposite tooth; there is no adjacent tooth contact; 3. There is systemic disease; there is severe periodontal disease, root loosening is more than II degree; internal absorption; external absorption; severe calcification of the root canal and atresia of the pulp cavity.

Design outcomes

Primary

MeasureTime frame
The electrovibrant pulp;Imaging check;Clinical symptoms;Temperature test;

Countries

China

Contacts

Public ContactHe Wenxi

The Third Affiliated Hospital of The Fourth Military Medical University

2624497165@qq.com+86 15991743898

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026