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A multi-center clinical trial study on the effect of Er:YAG laser combined with CGF pulpotomy in the treatment of irreversible pulpitis in mature permanent teeth

A multi-center clinical trial study on the effect of Er:YAG laser combined with CGF pulpotomy in the treatment of irreversible pulpitis in mature permanent teeth

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050775
Enrollment
Unknown
Registered
2021-09-04
Start date
2021-09-10
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpitis

Interventions

Group 1:pulpotomy
Group 2:Er:YAG laser
Group 3:CGF pulpotomy
Group 4:Er:YAG+CGF pulpotomy

Sponsors

The Third Affiliated Hospital of The Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Between the ages of 18 and 75, deep or very deep; 2.Grinding or front grinding teeth (tooth roots have been fully developed), there are symptoms of irreversible pulpitis (spontaneous pain history cold stimulation continues to stimulate pain exists or there is no bite pain), X-rays show the root tip of the normal root tip membrane cavity widening or root tip shadow.

Exclusion criteria

Exclusion criteria: 1. The tooth has crown or root fracture; it cannot be directly repaired; there is no opposite tooth; there is no adjacent tooth contact; 2. The existence of systemic disease; the existence of chronic periodontal disease; apical swelling; fistula; periodontal discharge; abnormal root loosening; internal absorption; external absorption; severe calcification of the root canal and atresia of the pulp cavity; 3. No bleeding in pulp exposure; pulp bleeding could not be controlled within 5 minutes with 2.5% sodium hypochlorite.

Design outcomes

Primary

MeasureTime frame
The electrovibrant pulp;Imaging check;Temperature test;Clinical symptoms;

Countries

China

Contacts

Public ContactHe Wenxi

The Third Affiliated Hospital of The Fourth Military Medical University

2624497165@qq.com+86 15991743898

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026